The investigational, non-stimulant ADHD treatment SPN-812 (viloxazine extended-release capsules) met its primary endpoint in a pivotal phase III study, showing a significant improvement in symptoms in children ages 6 to 11. (Clinical Therapeutics)
Although Kundalini yoga appeared to curb anxiety in adults, it wasn’t quite on par with cognitive behavioral therapy in a randomized trial. (JAMA Psychiatry)
Autism was up to six times more common among transgender and gender-diverse adults compared with cisgender adults in a new study of over 600,000 individuals. “Understanding how autism manifests in transgender and gender-diverse people will enrich our knowledge about autism in relation to gender and sex,” said co-author Meng-Chuan Lai, MD, PhD, of the University of Toronto. (Nature Communications)
Former First Lady Michelle Obama recently revealed she’s battling “low-grade depression.” (CNN)
Some of the top PTSD predictors in police officers? Displays of anxiety and depression early in their careers and a tendency to startle at sudden sounds. (ScienceDaily)
A small trial found ketamine suppressed glutamate and glutamine in the ventro-medial prefrontal cortex in people with depression, and thus could be used as biomarkers for rapid antidepressant effects. (JAMA Network Open)
Chloroquine was tied to a slew of neuropsychiatric adverse events, including amnesia, delirium, hallucinations, depression, and loss of consciousness. However, it wasn’t linked with suicide, psychosis, confusion, or agitation. (The Journal of Clinical Psychiatry)
Lundbeck halted its phase II study of the investigational schizophrenia drug Lu AF11167, a selective inhibitor of phosphodiesterase-10A, when an interim analysis indicated it would miss the primary endpoint.