‘Alarming’ CRC Hotspots; A Pandemic Opportunity; Microbubble Cancer Therapy?


New research shows an “alarming trend of increasing rates” of colorectal cancer (CRC) in young Black men living in certain hotspots, including west-central Appalachia, the lower Mississippi Delta, and eastern Virginia/North Carolina. (Huntsman Cancer Institute, American Journal of Cancer Research)

Could at-home HPV and cervical cancer screening be as accurate as office-based screening from a clinician? The National Cancer Institute plans to find out. (Kaiser Health News)

Another busy week at the FDA, with new first-line immunotherapy approvals in metastatic bladder and colorectal cancers, as well as approval of an at-home subcutaneous therapy for women with HER2-positive breast cancer.

Black patients with early-stage esophageal cancer are less likely to undergo surgery than whites, researchers found. (Thomas Jefferson University, Journal of Gastrointestinal Surgery)

Incorporating radiomics in lung cancer screening may help identify early-stage patients at risk of poor outcomes. (Moffitt Cancer Center, Nature Scientific Reports)

In findings presented at the virtual European Society for Medical Oncology World Congress on GI Cancer, age alone did not appear to impact the efficacy of olaparib (Lynparza) maintenance in patients with metastatic pancreatic cancer and germline BRCA mutations.

Screening for dental infections in acute myeloid leukemia (AML) patients led to a sixfold reduction in dental emergencies during induction chemotherapy. (JCO Oncology Practice)

After an interim analysis, a phase III trial studying pracinostat in AML was halted for lack of efficacy, said the Helsinn Group and MEI Pharma.

While Seattle Genetics announced positive topline results from its phase II innovaTV 204 trial, with tisotumab vedotin demonstrating a 24% response rate and median duration of response of over 8 months in women with pretreated metastatic cervical cancer.

Does the current pandemic present a unique opportunity to reduce or permanently eliminate unnecessary testing, office visits, and other low-value practices in cancer care? (JAMA Oncology)

Hospitalization after radiation therapy for head and neck cancer predicted worse cancer-specific and overall survival, according to research from Roswell Park Comprehensive Cancer Center. (Oral Oncology)

Often used for patients with cardiovascular disease, the MRI technique known as T1 mapping has been shown to spot aggressive tumors in children with neuroblastomas, as well as the efficacy of targeted agents. (Institute of Cancer Research, Cancer Research)

More than half of cancer survivors overestimate how healthy their eating habits are. (George Mason University, European Journal of Clinical Nutrition)

New research offers an alternate explanation for why naked mole rats rarely get cancer. (Cancer Research U.K., Nature)

Looking for a new gig? The American Society of Clinical Oncology is searching for its new chief medical officer following the recent announcement that Richard Schilsky, MD, will retire in early 2021. (ASCO Connection)

First came checkpoint inhibitors, then CAR T-cell therapy, are microbubbles the next cancer therapy breakthrough? (Forbes)

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    Ian Ingram joined MedPage Today in 2018 as Deputy Managing Editor, and covers oncology for the site.

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